It is expensive to compute residual diffusivity in chaotic in-compressible flows by solving advection-diffusion equation due to the formation of sharp internal layers in the advection dominated regime. Proper orthogonal decomposition (POD) is a classical method to construct a small number of adaptive orthogonal basis vectors for low cost computation based on snapshots of fully resolved solutions at a particular molecular diffusivity $D_{0}^{*}$... The quality of POD basis deteriorates if it is applied to $D_0\ll D_{0}^{*}$. To improve POD, we adapt a super-resolution generative adversarial deep neural network (SRGAN) to train a nonlinear mapping based on snapshot data at two values of $D_{0}^{*}$. The mapping models the sharpening effect on internal layers as $D_0$ becomes smaller. We show through numerical experiments that after applying such a mapping to snapshots, the prediction accuracy of residual diffusivity improves considerably that of the standard POD. (read more)