Density Dependent Cohesion Leads to Controlled Phase Separation in Brownian Suspensions

28 Nov 2017  ·  Melaugh Gavin, Marenduzzo Davide, Morozov Alexander, Allen Rosalind J. ·

Mechanical interactions between biological cells may be mediated by secreted products, making them dependent on the local particle density. Here, we explore the generic physics of density-dependent attractive interactions... We show using Brownian dynamics simulations that density-dependent interactions can produce interesting phase separation behaviour including control of aggregate size during a spinodal decomposition-like separation process. We show that these results are generic using continuum modelling of the appropriate Cahn-Hilliard equation. Our study suggests that density-dependent interactions can provide a generic mechanism for control of aggregate size during phase separation. read more

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Soft Condensed Matter