Our research objective is to understand the influence of geochemistry on the fracture behavior of organic-rich shale at multiple length-scales. Despite an increasing focus on the fracture behavior of organic-rich shale, the relationships between geochemistry and fracture behavior remain unclear and there is a scarcity of experimental data available... To this end, we carry out 59 mesoscale scratch-based fracture tests on 14 specimens extracted from 7 major gas shale plays both in the United States and in France. Post-scratch testing imaging reveal fractures with small crack width of about 400 nm. The fracture toughness is evaluated using the energetic size effect law, which is extended to generic axisymmetric probes. A nonlinear anisotropic and multiscale fracture behavior is observed. In addition, a positive correlation is found between the fracture toughness and the presence of of kerogen, clay and calcite. Moreover, the geochemistry is found to influence the timescale and the regime of propagation of the hydraulic fracture at the macroscopic length-scale. In particular, shale systems rich in TOC, clay and calcite are more likely to exhibit high values of the fluid lag and low hydraulic crack width. Our findings highlight the need for advanced constitutive models for organic-rich shale systems and advanced hydraulic fracturing solutions that can fully integrate the complex fracture response of organic-rich shale materials. (read more)