To establish a time reference frame between two users in quantum key distribution, a synchronization calibration process is usually applied for the case of using gated mode single-photon detectors (SPDs). Traditionally, the synchronization calibration is independently implemented by the line length measurement for each SPD... However, this will leave a loophole which has been experimentally demonstrated by a special attack. Here, we propose an alternative synchronization scheme by fixing the relative delay of the signal time window among all SPDs and jointly performing the line length measurement with multiple SPDs under combining low-precision with high-precision synchronization. The new scheme is not only immune to the vulnerability but also improves the synchronization time from usually a few seconds to tens of milliseconds. (read more)