Protein design by multiobjective optimization: evolutionary and non-evolutionary approaches

no code implementations • 1 Jul 2017 • 01 July 2017Sandeep V. Belure, Ofer M. Shir, Vikas Nanda

We formulate a bi-objective combinatorial minimization problem that targets both stability and specificity of the 4-level heterotrimer.

Combinatorial Optimization Efficient Exploration +3