no code implementations • 24 Feb 2024 • Ruth Johnson, Bogdan Pasaniuc
Precision medicine aims to create biomedical solutions tailored to specific factors that affect disease risk and treatment responses within the population.
no code implementations • 6 May 2023 • Helen Shang, Yi Ding, Vidhya Venkateswaran, Kristin Boulier, Nikhita Kathuria-Prakash, Parisa Boodaghi Malidarreh, Jacob M. Luber, Bogdan Pasaniuc
We found that the PRS313 achieved overlapping Areas under the ROC Curve (AUCs) in females of Lantix (AUC, 0. 68; 95 CI, 0. 65-0. 71) and European ancestry (AUC, 0. 70; 95 CI, 0. 69-0. 71) but lower AUCs for the AFR and EAA populations (AFR: AUC, 0. 61; 95 CI, 0. 56-0. 65; EAA: AUC, 0. 64; 95 CI, 0. 60-0. 680).
no code implementations • 25 Jul 2022 • Arunabha Majumdar, Bogdan Pasaniuc
However, evaluating polygenicity at the gene level can be biologically more meaningful.