no code implementations • 26 Oct 2020 • Gang Wang, Qunxi Dong, Jianfeng Wu, Yi Su, Kewei Chen, Qingtang Su, Xiaofeng Zhang, Jinguang Hao, Tao Yao, Li Liu, Caiming Zhang, Richard J Caselli, Eric M Reiman, Yalin Wang
With hippocampal UMIs, the estimated minimum sample sizes needed to detect a 25$\%$ reduction in the mean annual change with 80$\%$ power and two-tailed $P=0. 05$ are 116, 279 and 387 for the longitudinal $A\beta+$ AD, $A\beta+$ mild cognitive impairment (MCI) and $A\beta+$ CU groups, respectively.