Synergizing Data Imputation and Electronic Health Records for Advancing Prostate Cancer Research: Challenges, and Practical Applications

no code implementations • 24 Oct 2023 • Abderrahim Oussama Batouche, Eugen Czeizler, Miika Koskinen, Tuomas Mirtti, Antti Sakari Rannikko

The objective is to exploit the inherent redundancies available within the integrated structured and unstructured data entries within EHRs in order to generate comprehensive and reliable medical databases, ready to be used in advanced research studies.

Imputation Retrieval

Network analytics for drug repurposing in COVID-19

no code implementations • 23 Jun 2021 • Nicoleta Siminea, Victor Popescu, Jose Angel Sanchez Martin, Daniela Florea, Georgiana Gavril, Ana-Maria Gheorghe, Corina Itcus, Krishna Kanhaiya, Octavian Pacioglu, Laura Ioana Popa, Romica Trandafir, Maria Iris Tusa, Manuela Sidoroff, Mihaela Paun, Eugen Czeizler, Andrei Paun, Ion Petre

To better understand the potential of drug repurposing in COVID-19, we analyzed control strategies over essential host factors for SARS-CoV-2 infection.

Network modeling methods for precision medicine

no code implementations • 19 Apr 2021 • Elio Nushi, Victor-Bogdan Popescu, Jose Angel Sanchez Martin, Sergiu Ivanov, Eugen Czeizler, Ion Petre

We discuss in this survey several network modeling methods and their applicability to precision medicine.

Identifying efficient controls of complex interaction networks using genetic algorithms

no code implementations • 9 Jul 2020 • Victor-Bogdan Popescu, Krishna Kanhaiya, Iulian Năstac, Eugen Czeizler, Ion Petre

We tailor our solution for applications in computational drug repurposing, seeking to maximise its use of FDA-approved drug targets in a given disease-specific protein-protein interaction network.