The 3D Structural Phenotype of the Glaucomatous Optic Nerve Head and its Relationship with The Severity of Visual Field Damage

no code implementations • 7 Jan 2023 • Fabian A. Braeu, Thanadet Chuangsuwanich, Tin A. Tun, Shamira A. Perera, Rahat Husain, Aiste Kadziauskiene, Leopold Schmetterer, Alexandre H. Thiéry, George Barbastathis, Tin Aung, Michaël J. A. Girard

In both approaches, we observed that structural changes were more prominent in the superior and inferior quadrant of the ONH, particularly in the RNFL, the prelamina, and the LC.

AI-based Clinical Assessment of Optic Nerve Head Robustness Superseding Biomechanical Testing

no code implementations • 9 Jun 2022 • Fabian A. Braeu, Thanadet Chuangsuwanich, Tin A. Tun, Alexandre H. Thiery, Tin Aung, George Barbastathis, Michaël J. A. Girard

$\mathbf{Conclusions}$: We propose an AI-driven approach that can assess the robustness of a given ONH solely from a single OCT scan of the ONH, and without the need to perform biomechanical testing.

Geometric Deep Learning to Identify the Critical 3D Structural Features of the Optic Nerve Head for Glaucoma Diagnosis

no code implementations • 14 Apr 2022 • Fabian A. Braeu, Alexandre H. Thiéry, Tin A. Tun, Aiste Kadziauskiene, George Barbastathis, Tin Aung, Michaël J. A. Girard

To this end, we aimed: (1) To compare the performance of two relatively recent geometric deep learning techniques in diagnosing glaucoma from a single OCT scan of the ONH; and (2) To identify the 3D structural features of the ONH that are critical for the diagnosis of glaucoma.

A homogenized constrained mixture model of cardiac growth and remodeling: Analyzing mechanobiological stability and reversal

no code implementations • 23 Mar 2022 • Amadeus M. Gebauer, Martin R. Pfaller, Fabian A. Braeu, Christian J. Cyron, Wolfgang A. Wall

We propose a novel microstructure-motivated model that predicts organ-scale G&R in the heart based on the homogenized constrained mixture theory.