Model-based cellular kinetic analysis of SARS-CoV-2 infection: different immune response modes and treatment strategies

no code implementations • 12 Jan 2021 • Zhengqing Zhou, Zhiheng Zhao, Shuyu Shi, Jianghua Wu, Dianjie Li, Jianwei Li, Jingpeng Zhang, Ke Gui, Yu Zhang, Heng Mei, Yu Hu, Qi Ouyang, Fangting Li

Integrating theoretical results with clinical COVID-19 patients' data, we classified the COVID-19 development processes into three typical modes of immune responses, correlated with the clinical classification of mild & moderate, severe and critical patients.

Nonequilibrium and nonlinear kinetics as key determinants for bistability in fission yeast G2-M transition

no code implementations • 30 Oct 2016 • De Zhao, Teng Wang, Jian Zhao, Dianjie Li, Zhili Lin, Zeyan Chen, Qi Ouyang, Hong Qian, Yu V. Fu, Fangting Li

A living cell is an open, nonequilibrium biochemical system where ATP hydrolysis serves as the energy source for a wide range of intracellular processes, possibly including the assurance for decision-making.

Decision Making