Search Results for author: G. Tiana

Found 4 papers, 1 papers with code

Structure of the space of folding protein sequences defined by large language models

no code implementations10 Nov 2023 A. Zambon, R. Zecchina, G. Tiana

Our tool combines advancements in machine learning and statistical physics, providing new insights into the exploration of sequence landscapes where wide, flat minima coexist alongside a majority of narrower minima.

Locality of contacts determines the subdiffusion exponents in polymeric models of chromatin

no code implementations14 Jun 2023 E. Marchi, Y. Zhan, G. Tiana

With a simple polymeric model, we show that such a Rouse-like dynamics occurs when the parameters of the model are chosen so that contacts are local along the chain, while in presence of non-local contacts, we observe subdiffusion at short time scales with exponents smaller than 0. 5.

Key interaction patterns in proteins revealed by cluster expansion of the partition function

no code implementations8 Apr 2022 M. Tajana, A. Trovato, G. Tiana

The native conformation of structured proteins is stabilized by a complex network of interactions.

Effective Model of Loop Extrusion Predicts Chromosomal Domains

1 code implementation14 May 2020 M. Crippa, Y. Zhan, G. Tiana

By averaging out the position of the extruder along the chain, we build an effective equilibrium model capable of reproducing experimental contact maps based solely on the positions of extrusion--blocking proteins.

Blocking Position

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