no code implementations • 4 Mar 2024 • Sebastien Baur, Zaid Nabulsi, Wei-Hung Weng, Jake Garrison, Louis Blankemeier, Sam Fishman, Christina Chen, Sujay Kakarmath, Minyoi Maimbolwa, Nsala Sanjase, Brian Shuma, Yossi Matias, Greg S. Corrado, Shwetak Patel, Shravya Shetty, Shruthi Prabhakara, Monde Muyoyeta, Diego Ardila
Health acoustic sounds such as coughs and breaths are known to contain useful health signals with significant potential for monitoring health and disease, yet are underexplored in the medical machine learning community.
no code implementations • 23 Feb 2024 • Rajeev V. Rikhye, Aaron Loh, Grace Eunhae Hong, Preeti Singh, Margaret Ann Smith, Vijaytha Muralidharan, Doris Wong, Rory Sayres, Michelle Phung, Nicolas Betancourt, Bradley Fong, Rachna Sahasrabudhe, Khoban Nasim, Alec Eschholz, Basil Mustafa, Jan Freyberg, Terry Spitz, Yossi Matias, Greg S. Corrado, Katherine Chou, Dale R. Webster, Peggy Bui, YuAn Liu, Yun Liu, Justin Ko, Steven Lin
Recently, there has been great progress in the ability of artificial intelligence (AI) algorithms to classify dermatological conditions from clinical photographs.
no code implementations • 20 Oct 2023 • Jeremy Lai, Faruk Ahmed, Supriya Vijay, Tiam Jaroensri, Jessica Loo, Saurabh Vyawahare, Saloni Agarwal, Fayaz Jamil, Yossi Matias, Greg S. Corrado, Dale R. Webster, Jonathan Krause, Yun Liu, Po-Hsuan Cameron Chen, Ellery Wulczyn, David F. Steiner
Foundation models in histopathology that learn general representations across a wide range of tissue types, diagnoses, and magnifications offer the potential to reduce the data, compute, and technical expertise necessary to develop task-specific deep learning models with the required level of model performance.
no code implementations • 2 Aug 2023 • Shawn Xu, Lin Yang, Christopher Kelly, Marcin Sieniek, Timo Kohlberger, Martin Ma, Wei-Hung Weng, Atilla Kiraly, Sahar Kazemzadeh, Zakkai Melamed, Jungyeon Park, Patricia Strachan, Yun Liu, Chuck Lau, Preeti Singh, Christina Chen, Mozziyar Etemadi, Sreenivasa Raju Kalidindi, Yossi Matias, Katherine Chou, Greg S. Corrado, Shravya Shetty, Daniel Tse, Shruthi Prabhakara, Daniel Golden, Rory Pilgrim, Krish Eswaran, Andrew Sellergren
In this work, we present an approach, which we call Embeddings for Language/Image-aligned X-Rays, or ELIXR, that leverages a language-aligned image encoder combined or grafted onto a fixed LLM, PaLM 2, to perform a broad range of chest X-ray tasks.
no code implementations • 26 Jul 2023 • Tao Tu, Shekoofeh Azizi, Danny Driess, Mike Schaekermann, Mohamed Amin, Pi-Chuan Chang, Andrew Carroll, Chuck Lau, Ryutaro Tanno, Ira Ktena, Basil Mustafa, Aakanksha Chowdhery, Yun Liu, Simon Kornblith, David Fleet, Philip Mansfield, Sushant Prakash, Renee Wong, Sunny Virmani, Christopher Semturs, S Sara Mahdavi, Bradley Green, Ewa Dominowska, Blaise Aguera y Arcas, Joelle Barral, Dale Webster, Greg S. Corrado, Yossi Matias, Karan Singhal, Pete Florence, Alan Karthikesalingam, Vivek Natarajan
While considerable work is needed to validate these models in real-world use cases, our results represent a milestone towards the development of generalist biomedical AI systems.
1 code implementation • 5 Jul 2023 • David Stutz, Ali Taylan Cemgil, Abhijit Guha Roy, Tatiana Matejovicova, Melih Barsbey, Patricia Strachan, Mike Schaekermann, Jan Freyberg, Rajeev Rikhye, Beverly Freeman, Javier Perez Matos, Umesh Telang, Dale R. Webster, YuAn Liu, Greg S. Corrado, Yossi Matias, Pushmeet Kohli, Yun Liu, Arnaud Doucet, Alan Karthikesalingam
In contrast, we propose a framework where aggregation is done using a statistical model.
no code implementations • 1 Jun 2023 • Oran Lang, Doron Yaya-Stupp, Ilana Traynis, Heather Cole-Lewis, Chloe R. Bennett, Courtney Lyles, Charles Lau, Christopher Semturs, Dale R. Webster, Greg S. Corrado, Avinatan Hassidim, Yossi Matias, Yun Liu, Naama Hammel, Boris Babenko
In this paper, we present a method for automatic visual explanations leveraging team-based expertise by generating hypotheses of what visual signals in the images are correlated with the task.
no code implementations • 16 May 2023 • Karan Singhal, Tao Tu, Juraj Gottweis, Rory Sayres, Ellery Wulczyn, Le Hou, Kevin Clark, Stephen Pfohl, Heather Cole-Lewis, Darlene Neal, Mike Schaekermann, Amy Wang, Mohamed Amin, Sami Lachgar, Philip Mansfield, Sushant Prakash, Bradley Green, Ewa Dominowska, Blaise Aguera y Arcas, Nenad Tomasev, Yun Liu, Renee Wong, Christopher Semturs, S. Sara Mahdavi, Joelle Barral, Dale Webster, Greg S. Corrado, Yossi Matias, Shekoofeh Azizi, Alan Karthikesalingam, Vivek Natarajan
Large language models (LLMs) have catalyzed significant progress in medical question answering; Med-PaLM was the first model to exceed a "passing" score in US Medical Licensing Examination (USMLE) style questions with a score of 67. 2% on the MedQA dataset.
no code implementations • 9 May 2023 • Wei-Hung Weng, Sebastien Baur, Mayank Daswani, Christina Chen, Lauren Harrell, Sujay Kakarmath, Mariam Jabara, Babak Behsaz, Cory Y. McLean, Yossi Matias, Greg S. Corrado, Shravya Shetty, Shruthi Prabhakara, Yun Liu, Goodarz Danaei, Diego Ardila
We compared the DLS with the office-based refit-WHO score, which adopts the shared predictors from WHO and Globorisk scores (age, sex, smoking status, height, weight and systolic blood pressure) but refitted on the UK Biobank (UKB) cohort.
no code implementations • 26 Dec 2022 • Karan Singhal, Shekoofeh Azizi, Tao Tu, S. Sara Mahdavi, Jason Wei, Hyung Won Chung, Nathan Scales, Ajay Tanwani, Heather Cole-Lewis, Stephen Pfohl, Perry Payne, Martin Seneviratne, Paul Gamble, Chris Kelly, Nathaneal Scharli, Aakanksha Chowdhery, Philip Mansfield, Blaise Aguera y Arcas, Dale Webster, Greg S. Corrado, Yossi Matias, Katherine Chou, Juraj Gottweis, Nenad Tomasev, Yun Liu, Alvin Rajkomar, Joelle Barral, Christopher Semturs, Alan Karthikesalingam, Vivek Natarajan
To resolve this we introduce instruction prompt tuning, a parameter-efficient approach for aligning LLMs to new domains using a few exemplars.
Ranked #4 on Multiple Choice Question Answering (MCQA) on MedMCQA (Dev Set (Acc-%) metric)
no code implementations • 19 Jul 2022 • Boris Babenko, Ilana Traynis, Christina Chen, Preeti Singh, Akib Uddin, Jorge Cuadros, Lauren P. Daskivich, April Y. Maa, Ramasamy Kim, Eugene Yu-Chuan Kang, Yossi Matias, Greg S. Corrado, Lily Peng, Dale R. Webster, Christopher Semturs, Jonathan Krause, Avinash V. Varadarajan, Naama Hammel, Yun Liu
On validation sets B and C, with substantial patient population differences compared to the development sets, the DLS outperformed the baseline for ACR>=300 and Hgb<11 by 7. 3-13. 2%.
2 code implementations • 19 May 2022 • Shekoofeh Azizi, Laura Culp, Jan Freyberg, Basil Mustafa, Sebastien Baur, Simon Kornblith, Ting Chen, Patricia MacWilliams, S. Sara Mahdavi, Ellery Wulczyn, Boris Babenko, Megan Wilson, Aaron Loh, Po-Hsuan Cameron Chen, YuAn Liu, Pinal Bavishi, Scott Mayer McKinney, Jim Winkens, Abhijit Guha Roy, Zach Beaver, Fiona Ryan, Justin Krogue, Mozziyar Etemadi, Umesh Telang, Yun Liu, Lily Peng, Greg S. Corrado, Dale R. Webster, David Fleet, Geoffrey Hinton, Neil Houlsby, Alan Karthikesalingam, Mohammad Norouzi, Vivek Natarajan
These results suggest that REMEDIS can significantly accelerate the life-cycle of medical imaging AI development thereby presenting an important step forward for medical imaging AI to deliver broad impact.
no code implementations • 16 May 2021 • Sahar Kazemzadeh, Jin Yu, Shahar Jamshy, Rory Pilgrim, Zaid Nabulsi, Christina Chen, Neeral Beladia, Charles Lau, Scott Mayer McKinney, Thad Hughes, Atilla Kiraly, Sreenivasa Raju Kalidindi, Monde Muyoyeta, Jameson Malemela, Ting Shih, Greg S. Corrado, Lily Peng, Katherine Chou, Po-Hsuan Cameron Chen, Yun Liu, Krish Eswaran, Daniel Tse, Shravya Shetty, Shruthi Prabhakara
Tuberculosis (TB) is a top-10 cause of death worldwide.
no code implementations • 8 Apr 2021 • Abhijit Guha Roy, Jie Ren, Shekoofeh Azizi, Aaron Loh, Vivek Natarajan, Basil Mustafa, Nick Pawlowski, Jan Freyberg, YuAn Liu, Zach Beaver, Nam Vo, Peggy Bui, Samantha Winter, Patricia MacWilliams, Greg S. Corrado, Umesh Telang, Yun Liu, Taylan Cemgil, Alan Karthikesalingam, Balaji Lakshminarayanan, Jim Winkens
We develop and rigorously evaluate a deep learning based system that can accurately classify skin conditions while detecting rare conditions for which there is not enough data available for training a confident classifier.
no code implementations • 25 Nov 2020 • Ellery Wulczyn, Kunal Nagpal, Matthew Symonds, Melissa Moran, Markus Plass, Robert Reihs, Farah Nader, Fraser Tan, Yuannan Cai, Trissia Brown, Isabelle Flament-Auvigne, Mahul B. Amin, Martin C. Stumpe, Heimo Muller, Peter Regitnig, Andreas Holzinger, Greg S. Corrado, Lily H. Peng, Po-Hsuan Cameron Chen, David F. Steiner, Kurt Zatloukal, Yun Liu, Craig H. Mermel
's C-indices were 0. 87 and 0. 85 for continuous and discrete grading, respectively, compared to 0. 79 (95%CI 0. 71-0. 86) for GG obtained from the reports.
no code implementations • 23 Nov 2020 • Boris Babenko, Akinori Mitani, Ilana Traynis, Naho Kitade, Preeti Singh, April Maa, Jorge Cuadros, Greg S. Corrado, Lily Peng, Dale R. Webster, Avinash Varadarajan, Naama Hammel, Yun Liu
In validation set A (n=27, 415 patients, all undilated), the DLS detected poor blood glucose control (HbA1c > 9%) with an area under receiver operating characteristic curve (AUC) of 70. 2; moderate-or-worse DR with an AUC of 75. 3; diabetic macular edema with an AUC of 78. 0; and vision-threatening DR with an AUC of 79. 4.
no code implementations • 17 Nov 2020 • Ellery Wulczyn, David F. Steiner, Melissa Moran, Markus Plass, Robert Reihs, Fraser Tan, Isabelle Flament-Auvigne, Trissia Brown, Peter Regitnig, Po-Hsuan Cameron Chen, Narayan Hegde, Apaar Sadhwani, Robert MacDonald, Benny Ayalew, Greg S. Corrado, Lily H. Peng, Daniel Tse, Heimo Müller, Zhaoyang Xu, Yun Liu, Martin C. Stumpe, Kurt Zatloukal, Craig H. Mermel
Our approach can be used to explain predictions from a prognostic deep learning model and uncover potentially-novel prognostic features that can be reliably identified by people for future validation studies.
no code implementations • 22 Oct 2020 • Zaid Nabulsi, Andrew Sellergren, Shahar Jamshy, Charles Lau, Edward Santos, Atilla P. Kiraly, Wenxing Ye, Jie Yang, Rory Pilgrim, Sahar Kazemzadeh, Jin Yu, Sreenivasa Raju Kalidindi, Mozziyar Etemadi, Florencia Garcia-Vicente, David Melnick, Greg S. Corrado, Lily Peng, Krish Eswaran, Daniel Tse, Neeral Beladia, Yun Liu, Po-Hsuan Cameron Chen, Shravya Shetty
To assess generalizability, we evaluated our system using 6 international datasets from India, China, and the United States.
no code implementations • 10 Aug 2020 • Ashish Bora, Siva Balasubramanian, Boris Babenko, Sunny Virmani, Subhashini Venugopalan, Akinori Mitani, Guilherme de Oliveira Marinho, Jorge Cuadros, Paisan Ruamviboonsuk, Greg S. Corrado, Lily Peng, Dale R. Webster, Avinash V. Varadarajan, Naama Hammel, Yun Liu, Pinal Bavishi
We created and validated two versions of a deep learning system (DLS) to predict the development of mild-or-worse ("Mild+") DR in diabetic patients undergoing DR screening.
no code implementations • 11 Sep 2019 • Yuan Liu, Ayush Jain, Clara Eng, David H. Way, Kang Lee, Peggy Bui, Kimberly Kanada, Guilherme de Oliveira Marinho, Jessica Gallegos, Sara Gabriele, Vishakha Gupta, Nalini Singh, Vivek Natarajan, Rainer Hofmann-Wellenhof, Greg S. Corrado, Lily H. Peng, Dale R. Webster, Dennis Ai, Susan Huang, Yun Liu, R. Carter Dunn, David Coz
In this paper, we developed a deep learning system (DLS) to provide a differential diagnosis of skin conditions for clinical cases (skin photographs and associated medical histories).
no code implementations • 12 Apr 2019 • Akinori Mitani, Yun Liu, Abigail Huang, Greg S. Corrado, Lily Peng, Dale R. Webster, Naama Hammel, Avinash V. Varadarajan
Despite its high prevalence, anemia is often undetected due to the invasiveness and cost of screening and diagnostic tests.
no code implementations • 10 Apr 2019 • Boris Babenko, Siva Balasubramanian, Katy E. Blumer, Greg S. Corrado, Lily Peng, Dale R. Webster, Naama Hammel, Avinash V. Varadarajan
For predicting progression specifically from iAMD, the DL algorithm's sensitivity (57+/-6%) was also higher compared to the 9-step grades (36+/-8%) and the 4-category grades (20+/-0%).
no code implementations • 30 Jan 2019 • Narayan Hegde, Jason D. Hipp, Yun Liu, Michael E. Buck, Emily Reif, Daniel Smilkov, Michael Terry, Carrie J. Cai, Mahul B. Amin, Craig H. Mermel, Phil Q. Nelson, Lily H. Peng, Greg S. Corrado, Martin C. Stumpe
SMILY may be a useful general-purpose tool in the pathologist's arsenal, to improve the efficiency of searching large archives of histopathology images, without the need to develop and implement specific tools for each application.
no code implementations • 21 Dec 2018 • Sonia Phene, R. Carter Dunn, Naama Hammel, Yun Liu, Jonathan Krause, Naho Kitade, Mike Schaekermann, Rory Sayres, Derek J. Wu, Ashish Bora, Christopher Semturs, Anita Misra, Abigail E. Huang, Arielle Spitze, Felipe A. Medeiros, April Y. Maa, Monica Gandhi, Greg S. Corrado, Lily Peng, Dale R. Webster
An algorithm trained on fundus images alone can detect referable GON with higher sensitivity than and comparable specificity to eye care providers.
no code implementations • 21 Nov 2018 • Po-Hsuan Cameron Chen, Krishna Gadepalli, Robert MacDonald, Yun Liu, Kunal Nagpal, Timo Kohlberger, Jeffrey Dean, Greg S. Corrado, Jason D. Hipp, Martin C. Stumpe
We demonstrate the utility of ARM in the detection of lymph node metastases in breast cancer and the identification of prostate cancer with a latency that supports real-time workflows.
no code implementations • 15 Nov 2018 • Kunal Nagpal, Davis Foote, Yun Liu, Po-Hsuan, Chen, Ellery Wulczyn, Fraser Tan, Niels Olson, Jenny L. Smith, Arash Mohtashamian, James H. Wren, Greg S. Corrado, Robert MacDonald, Lily H. Peng, Mahul B. Amin, Andrew J. Evans, Ankur R. Sangoi, Craig H. Mermel, Jason D. Hipp, Martin C. Stumpe
For prostate cancer patients, the Gleason score is one of the most important prognostic factors, potentially determining treatment independent of the stage.
no code implementations • 18 Oct 2018 • Avinash Varadarajan, Pinal Bavishi, Paisan Raumviboonsuk, Peranut Chotcomwongse, Subhashini Venugopalan, Arunachalam Narayanaswamy, Jorge Cuadros, Kuniyoshi Kanai, George Bresnick, Mongkol Tadarati, Sukhum Silpa-archa, Jirawut Limwattanayingyong, Variya Nganthavee, Joe Ledsam, Pearse A. Keane, Greg S. Corrado, Lily Peng, Dale R. Webster
To improve the accuracy of DME screening, we trained a deep learning model to use color fundus photographs to predict ci-DME.
no code implementations • 18 Oct 2018 • Paisan Raumviboonsuk, Jonathan Krause, Peranut Chotcomwongse, Rory Sayres, Rajiv Raman, Kasumi Widner, Bilson J L Campana, Sonia Phene, Kornwipa Hemarat, Mongkol Tadarati, Sukhum Silpa-Acha, Jirawut Limwattanayingyong, Chetan Rao, Oscar Kuruvilla, Jesse Jung, Jeffrey Tan, Surapong Orprayoon, Chawawat Kangwanwongpaisan, Ramase Sukulmalpaiboon, Chainarong Luengchaichawang, Jitumporn Fuangkaew, Pipat Kongsap, Lamyong Chualinpha, Sarawuth Saree, Srirat Kawinpanitan, Korntip Mitvongsa, Siriporn Lawanasakol, Chaiyasit Thepchatri, Lalita Wongpichedchai, Greg S. Corrado, Lily Peng, Dale R. Webster
Deep learning algorithms have been used to detect diabetic retinopathy (DR) with specialist-level accuracy.
no code implementations • 21 Dec 2017 • Avinash V. Varadarajan, Ryan Poplin, Katy Blumer, Christof Angermueller, Joe Ledsam, Reena Chopra, Pearse A. Keane, Greg S. Corrado, Lily Peng, Dale R. Webster
Mean absolute error (MAE) of the algorithm's prediction compared to the refractive error obtained in the AREDS and UK Biobank.
no code implementations • 4 Oct 2017 • Jonathan Krause, Varun Gulshan, Ehsan Rahimy, Peter Karth, Kasumi Widner, Greg S. Corrado, Lily Peng, Dale R. Webster
Diabetic retinopathy (DR) and diabetic macular edema are common complications of diabetes which can lead to vision loss.
no code implementations • 31 Aug 2017 • Ryan Poplin, Avinash V. Varadarajan, Katy Blumer, Yun Liu, Michael V. McConnell, Greg S. Corrado, Lily Peng, Dale R. Webster
Traditionally, medical discoveries are made by observing associations and then designing experiments to test these hypotheses.
6 code implementations • 3 Mar 2017 • Yun Liu, Krishna Gadepalli, Mohammad Norouzi, George E. Dahl, Timo Kohlberger, Aleksey Boyko, Subhashini Venugopalan, Aleksei Timofeev, Philip Q. Nelson, Greg S. Corrado, Jason D. Hipp, Lily Peng, Martin C. Stumpe
At 8 false positives per image, we detect 92. 4% of the tumors, relative to 82. 7% by the previous best automated approach.
Ranked #2 on Medical Object Detection on Barrett’s Esophagus
4 code implementations • 14 Mar 2016 • Martín Abadi, Ashish Agarwal, Paul Barham, Eugene Brevdo, Zhifeng Chen, Craig Citro, Greg S. Corrado, Andy Davis, Jeffrey Dean, Matthieu Devin, Sanjay Ghemawat, Ian Goodfellow, Andrew Harp, Geoffrey Irving, Michael Isard, Yangqing Jia, Rafal Jozefowicz, Lukasz Kaiser, Manjunath Kudlur, Josh Levenberg, Dan Mane, Rajat Monga, Sherry Moore, Derek Murray, Chris Olah, Mike Schuster, Jonathon Shlens, Benoit Steiner, Ilya Sutskever, Kunal Talwar, Paul Tucker, Vincent Vanhoucke, Vijay Vasudevan, Fernanda Viegas, Oriol Vinyals, Pete Warden, Martin Wattenberg, Martin Wicke, Yuan Yu, Xiaoqiang Zheng
TensorFlow is an interface for expressing machine learning algorithms, and an implementation for executing such algorithms.
2 code implementations • 19 Dec 2013 • Mohammad Norouzi, Tomas Mikolov, Samy Bengio, Yoram Singer, Jonathon Shlens, Andrea Frome, Greg S. Corrado, Jeffrey Dean
In other cases the semantic embedding space is established by an independent natural language processing task, and then the image transformation into that space is learned in a second stage.
Ranked #8 on Multi-label zero-shot learning on Open Images V4
no code implementations • NeurIPS 2013 • Andrea Frome, Greg S. Corrado, Jon Shlens, Samy Bengio, Jeff Dean, Marc'Aurelio Ranzato, Tomas Mikolov
Modern visual recognition systems are often limited in their ability to scale to large numbers of object categories.
Ranked #13 on Zero-Shot Action Recognition on Kinetics
1 code implementation • 29 Dec 2011 • Quoc V. Le, Marc'Aurelio Ranzato, Rajat Monga, Matthieu Devin, Kai Chen, Greg S. Corrado, Jeff Dean, Andrew Y. Ng
For example, is it possible to learn a face detector using only unlabeled images?