no code implementations • 11 Jan 2024 • Tao Tu, Anil Palepu, Mike Schaekermann, Khaled Saab, Jan Freyberg, Ryutaro Tanno, Amy Wang, Brenna Li, Mohamed Amin, Nenad Tomasev, Shekoofeh Azizi, Karan Singhal, Yong Cheng, Le Hou, Albert Webson, Kavita Kulkarni, S Sara Mahdavi, Christopher Semturs, Juraj Gottweis, Joelle Barral, Katherine Chou, Greg S Corrado, Yossi Matias, Alan Karthikesalingam, Vivek Natarajan
The study included 149 case scenarios from clinical providers in Canada, the UK, and India, 20 PCPs for comparison with AMIE, and evaluations by specialist physicians and patient actors.
no code implementations • 30 Nov 2023 • Ryutaro Tanno, David G. T. Barrett, Andrew Sellergren, Sumedh Ghaisas, Sumanth Dathathri, Abigail See, Johannes Welbl, Karan Singhal, Shekoofeh Azizi, Tao Tu, Mike Schaekermann, Rhys May, Roy Lee, SiWai Man, Zahra Ahmed, Sara Mahdavi, Yossi Matias, Joelle Barral, Ali Eslami, Danielle Belgrave, Vivek Natarajan, Shravya Shetty, Pushmeet Kohli, Po-Sen Huang, Alan Karthikesalingam, Ira Ktena
Radiology reports are an instrumental part of modern medicine, informing key clinical decisions such as diagnosis and treatment.
no code implementations • 30 Nov 2023 • Daniel McDuff, Mike Schaekermann, Tao Tu, Anil Palepu, Amy Wang, Jake Garrison, Karan Singhal, Yash Sharma, Shekoofeh Azizi, Kavita Kulkarni, Le Hou, Yong Cheng, Yun Liu, S Sara Mahdavi, Sushant Prakash, Anupam Pathak, Christopher Semturs, Shwetak Patel, Dale R Webster, Ewa Dominowska, Juraj Gottweis, Joelle Barral, Katherine Chou, Greg S Corrado, Yossi Matias, Jake Sunshine, Alan Karthikesalingam, Vivek Natarajan
Comparing the two assisted study arms, the DDx quality score was higher for clinicians assisted by our LLM (top-10 accuracy 51. 7%) compared to clinicians without its assistance (36. 1%) (McNemar's Test: 45. 7, p < 0. 01) and clinicians with search (44. 4%) (4. 75, p = 0. 03).
no code implementations • 23 Aug 2023 • Sudipta Chattopadhyay, Srikant Sukumar, Vivek Natarajan
Several modifications of the model reference adaptive control (MRAC) framework have been proposed to address input constraints in uncertain linear systems.
no code implementations • 3 Aug 2023 • Isaac R. Galatzer-Levy, Daniel McDuff, Vivek Natarajan, Alan Karthikesalingam, Matteo Malgaroli
The current work investigates the capability of Large language models (LLMs) that are explicitly trained on large corpuses of medical knowledge (Med-PaLM 2) to predict psychiatric functioning from patient interviews and clinical descriptions without being trained to do so.
no code implementations • 26 Jul 2023 • Tao Tu, Shekoofeh Azizi, Danny Driess, Mike Schaekermann, Mohamed Amin, Pi-Chuan Chang, Andrew Carroll, Chuck Lau, Ryutaro Tanno, Ira Ktena, Basil Mustafa, Aakanksha Chowdhery, Yun Liu, Simon Kornblith, David Fleet, Philip Mansfield, Sushant Prakash, Renee Wong, Sunny Virmani, Christopher Semturs, S Sara Mahdavi, Bradley Green, Ewa Dominowska, Blaise Aguera y Arcas, Joelle Barral, Dale Webster, Greg S. Corrado, Yossi Matias, Karan Singhal, Pete Florence, Alan Karthikesalingam, Vivek Natarajan
While considerable work is needed to validate these models in real-world use cases, our results represent a milestone towards the development of generalist biomedical AI systems.
no code implementations • 21 May 2023 • Soham Chatterjee, Vivek Natarajan
We consider the problem of finding an input signal which transfers a linear boundary controlled 1D parabolic partial differential equation, with spatially-varying coefficients and a non-local term, from a given initial state to a desired final state.
no code implementations • 19 May 2023 • Sudipta Chattopadhyay, Srikant Sukumar, Vivek Natarajan
The unknown parameter can be reconstructed using the transfer function coefficient estimates obtained with n large and the algebraic expressions relating the transfer function coefficients to the unknown parameter.
no code implementations • 16 May 2023 • Karan Singhal, Tao Tu, Juraj Gottweis, Rory Sayres, Ellery Wulczyn, Le Hou, Kevin Clark, Stephen Pfohl, Heather Cole-Lewis, Darlene Neal, Mike Schaekermann, Amy Wang, Mohamed Amin, Sami Lachgar, Philip Mansfield, Sushant Prakash, Bradley Green, Ewa Dominowska, Blaise Aguera y Arcas, Nenad Tomasev, Yun Liu, Renee Wong, Christopher Semturs, S. Sara Mahdavi, Joelle Barral, Dale Webster, Greg S. Corrado, Yossi Matias, Shekoofeh Azizi, Alan Karthikesalingam, Vivek Natarajan
Large language models (LLMs) have catalyzed significant progress in medical question answering; Med-PaLM was the first model to exceed a "passing" score in US Medical Licensing Examination (USMLE) style questions with a score of 67. 2% on the MedQA dataset.
no code implementations • 26 Dec 2022 • Karan Singhal, Shekoofeh Azizi, Tao Tu, S. Sara Mahdavi, Jason Wei, Hyung Won Chung, Nathan Scales, Ajay Tanwani, Heather Cole-Lewis, Stephen Pfohl, Perry Payne, Martin Seneviratne, Paul Gamble, Chris Kelly, Nathaneal Scharli, Aakanksha Chowdhery, Philip Mansfield, Blaise Aguera y Arcas, Dale Webster, Greg S. Corrado, Yossi Matias, Katherine Chou, Juraj Gottweis, Nenad Tomasev, Yun Liu, Alvin Rajkomar, Joelle Barral, Christopher Semturs, Alan Karthikesalingam, Vivek Natarajan
To resolve this we introduce instruction prompt tuning, a parameter-efficient approach for aligning LLMs to new domains using a few exemplars.
Ranked #4 on Multiple Choice Question Answering (MCQA) on MedMCQA (Dev Set (Acc-%) metric)
2 code implementations • 19 May 2022 • Shekoofeh Azizi, Laura Culp, Jan Freyberg, Basil Mustafa, Sebastien Baur, Simon Kornblith, Ting Chen, Patricia MacWilliams, S. Sara Mahdavi, Ellery Wulczyn, Boris Babenko, Megan Wilson, Aaron Loh, Po-Hsuan Cameron Chen, YuAn Liu, Pinal Bavishi, Scott Mayer McKinney, Jim Winkens, Abhijit Guha Roy, Zach Beaver, Fiona Ryan, Justin Krogue, Mozziyar Etemadi, Umesh Telang, Yun Liu, Lily Peng, Greg S. Corrado, Dale R. Webster, David Fleet, Geoffrey Hinton, Neil Houlsby, Alan Karthikesalingam, Mohammad Norouzi, Vivek Natarajan
These results suggest that REMEDIS can significantly accelerate the life-cycle of medical imaging AI development thereby presenting an important step forward for medical imaging AI to deliver broad impact.
no code implementations • 2 Feb 2022 • Jessica Schrouff, Natalie Harris, Oluwasanmi Koyejo, Ibrahim Alabdulmohsin, Eva Schnider, Krista Opsahl-Ong, Alex Brown, Subhrajit Roy, Diana Mincu, Christina Chen, Awa Dieng, YuAn Liu, Vivek Natarajan, Alan Karthikesalingam, Katherine Heller, Silvia Chiappa, Alexander D'Amour
Diagnosing and mitigating changes in model fairness under distribution shift is an important component of the safe deployment of machine learning in healthcare settings.
1 code implementation • 29 Sep 2021 • Alexandros Karargyris, Renato Umeton, Micah J. Sheller, Alejandro Aristizabal, Johnu George, Srini Bala, Daniel J. Beutel, Victor Bittorf, Akshay Chaudhari, Alexander Chowdhury, Cody Coleman, Bala Desinghu, Gregory Diamos, Debo Dutta, Diane Feddema, Grigori Fursin, Junyi Guo, Xinyuan Huang, David Kanter, Satyananda Kashyap, Nicholas Lane, Indranil Mallick, Pietro Mascagni, Virendra Mehta, Vivek Natarajan, Nikola Nikolov, Nicolas Padoy, Gennady Pekhimenko, Vijay Janapa Reddi, G Anthony Reina, Pablo Ribalta, Jacob Rosenthal, Abhishek Singh, Jayaraman J. Thiagarajan, Anna Wuest, Maria Xenochristou, Daguang Xu, Poonam Yadav, Michael Rosenthal, Massimo Loda, Jason M. Johnson, Peter Mattson
Medical AI has tremendous potential to advance healthcare by supporting the evidence-based practice of medicine, personalizing patient treatment, reducing costs, and improving provider and patient experience.
no code implementations • 22 Apr 2021 • Aditya A. Paranjape, Vivek Natarajan, Supratim Ghosh
Adaptive control architectures often make use of Lyapunov functions to design adaptive laws.
no code implementations • 8 Apr 2021 • Abhijit Guha Roy, Jie Ren, Shekoofeh Azizi, Aaron Loh, Vivek Natarajan, Basil Mustafa, Nick Pawlowski, Jan Freyberg, YuAn Liu, Zach Beaver, Nam Vo, Peggy Bui, Samantha Winter, Patricia MacWilliams, Greg S. Corrado, Umesh Telang, Yun Liu, Taylan Cemgil, Alan Karthikesalingam, Balaji Lakshminarayanan, Jim Winkens
We develop and rigorously evaluate a deep learning based system that can accurately classify skin conditions while detecting rare conditions for which there is not enough data available for training a confident classifier.
no code implementations • 14 Jan 2021 • Basil Mustafa, Aaron Loh, Jan Freyberg, Patricia MacWilliams, Megan Wilson, Scott Mayer McKinney, Marcin Sieniek, Jim Winkens, YuAn Liu, Peggy Bui, Shruthi Prabhakara, Umesh Telang, Alan Karthikesalingam, Neil Houlsby, Vivek Natarajan
However, for medical imaging, the value of transfer learning is less clear.
1 code implementation • ICCV 2021 • Shekoofeh Azizi, Basil Mustafa, Fiona Ryan, Zachary Beaver, Jan Freyberg, Jonathan Deaton, Aaron Loh, Alan Karthikesalingam, Simon Kornblith, Ting Chen, Vivek Natarajan, Mohammad Norouzi
Self-supervised pretraining followed by supervised fine-tuning has seen success in image recognition, especially when labeled examples are scarce, but has received limited attention in medical image analysis.
no code implementations • 6 Nov 2020 • Alexander D'Amour, Katherine Heller, Dan Moldovan, Ben Adlam, Babak Alipanahi, Alex Beutel, Christina Chen, Jonathan Deaton, Jacob Eisenstein, Matthew D. Hoffman, Farhad Hormozdiari, Neil Houlsby, Shaobo Hou, Ghassen Jerfel, Alan Karthikesalingam, Mario Lucic, Yian Ma, Cory McLean, Diana Mincu, Akinori Mitani, Andrea Montanari, Zachary Nado, Vivek Natarajan, Christopher Nielson, Thomas F. Osborne, Rajiv Raman, Kim Ramasamy, Rory Sayres, Jessica Schrouff, Martin Seneviratne, Shannon Sequeira, Harini Suresh, Victor Veitch, Max Vladymyrov, Xuezhi Wang, Kellie Webster, Steve Yadlowsky, Taedong Yun, Xiaohua Zhai, D. Sculley
Predictors returned by underspecified pipelines are often treated as equivalent based on their training domain performance, but we show here that such predictors can behave very differently in deployment domains.
no code implementations • 9 Oct 2020 • Wei-Hung Weng, Jonathan Deaton, Vivek Natarajan, Gamaleldin F. Elsayed, YuAn Liu
Class imbalance is a common problem in medical diagnosis, causing a standard classifier to be biased towards the common classes and perform poorly on the rare classes.
no code implementations • 10 Jul 2020 • Jim Winkens, Rudy Bunel, Abhijit Guha Roy, Robert Stanforth, Vivek Natarajan, Joseph R. Ledsam, Patricia MacWilliams, Pushmeet Kohli, Alan Karthikesalingam, Simon Kohl, Taylan Cemgil, S. M. Ali Eslami, Olaf Ronneberger
Reliable detection of out-of-distribution (OOD) inputs is increasingly understood to be a precondition for deployment of machine learning systems.
Ranked #12 on Out-of-Distribution Detection on CIFAR-100 vs CIFAR-10
Out-of-Distribution Detection Out of Distribution (OOD) Detection
no code implementations • 20 Nov 2019 • Amirata Ghorbani, Vivek Natarajan, David Coz, Yu-An Liu
Despite the recent success in applying supervised deep learning to medical imaging tasks, the problem of obtaining large and diverse expert-annotated datasets required for the development of high performant models remains particularly challenging.
no code implementations • 11 Sep 2019 • Yuan Liu, Ayush Jain, Clara Eng, David H. Way, Kang Lee, Peggy Bui, Kimberly Kanada, Guilherme de Oliveira Marinho, Jessica Gallegos, Sara Gabriele, Vishakha Gupta, Nalini Singh, Vivek Natarajan, Rainer Hofmann-Wellenhof, Greg S. Corrado, Lily H. Peng, Dale R. Webster, Dennis Ai, Susan Huang, Yun Liu, R. Carter Dunn, David Coz
In this paper, we developed a deep learning system (DLS) to provide a differential diagnosis of skin conditions for clinical cases (skin photographs and associated medical histories).
7 code implementations • CVPR 2019 • Amanpreet Singh, Vivek Natarajan, Meet Shah, Yu Jiang, Xinlei Chen, Dhruv Batra, Devi Parikh, Marcus Rohrbach
We show that LoRRA outperforms existing state-of-the-art VQA models on our TextVQA dataset.
Ranked #3 on Visual Question Answering (VQA) on VizWiz 2018
9 code implementations • 26 Jul 2018 • Yu Jiang, Vivek Natarajan, Xinlei Chen, Marcus Rohrbach, Dhruv Batra, Devi Parikh
We demonstrate that by making subtle but important changes to the model architecture and the learning rate schedule, fine-tuning image features, and adding data augmentation, we can significantly improve the performance of the up-down model on VQA v2. 0 dataset -- from 65. 67% to 70. 22%.
Ranked #10 on Visual Question Answering (VQA) on A-OKVQA