1 code implementation • 9 Jun 2023 • Sean Cottrell, Rui Wang, GuoWei Wei
Over the years, Principal Component Analysis (PCA) has served as the baseline approach for dimensionality reduction in gene expression data analysis.
1 code implementation • 2 Nov 2022 • Hongsong Feng, GuoWei Wei
We are particularly interested in the hERG-cardiotoxicity of compounds collected in the DrugBank database considering that many DrugBank compounds have been approved for therapeutic treatments or have high potential to become drugs.
no code implementations • 13 Oct 2020 • Jiahui Chen, Kaifu Gao, Rui Wang, GuoWei Wei
This discovery implies the vulnerability of current vaccines and antibody drugs to new mutations.
no code implementations • 27 Aug 2017 • Zixuan Cang, Lin Mu, GuoWei Wei
This work introduces a number of algebraic topology approaches, such as multicomponent persistent homology, multi-level persistent homology and electrostatic persistence for the representation, characterization, and description of small molecules and biomolecular complexes.