no code implementations • 14 Jan 2024 • Yixuan Chen, Guoye Guan, Lei-Han Tang, Chao Tang
Once again, a generic set of kinetic parameters moves the interface towards either the anterior or posterior end, yet a polarized pattern can be stabilized through spatial tuning of one or more parameters coupled to intracellular or extracellular cues.
no code implementations • 12 May 2021 • Jiao Miao, Guoye Guan, Chao Tang
Gastrulation, namely cell internalization, is a significant milestone during the development of metazoans from worm to human, which generates multiple embryonic layers with distinct cell fates and spatial organizations.
no code implementations • 11 Jul 2020 • Guoye Guan, Ming-Kin Wong, Zhongying Zhao, Lei-Han Tang, Chao Tang
Nematode species are well-known for their invariant cell lineage pattern during development.