Search Results for author: Jenna M. Reps

Found 5 papers, 0 papers with code

How little data do we need for patient-level prediction?

no code implementations14 Aug 2020 Luis H. John, Jan A. Kors, Jenna M. Reps, Patrick B. Ryan, Peter R. Rijnbeek

Objective: Provide guidance on sample size considerations for developing predictive models by empirically establishing the adequate sample size, which balances the competing objectives of improving model performance and reducing model complexity as well as computational requirements.

Future prediction

Refining adverse drug reaction signals by incorporating interaction variables identified using emergent pattern mining

no code implementations20 Jul 2016 Jenna M. Reps, Uwe Aickelin, Richard B. Hubbard

We then implemented a cohort study design using regularised cox regression that incorporated and accounted for the candidate confounding interaction terms.

regression

Tuning a Multiple Classifier System for Side Effect Discovery using Genetic Algorithms

no code implementations3 Sep 2014 Jenna M. Reps, Uwe Aickelin, Jonathan M. Garibaldi

The results of this research show that the novel framework implementing a multiple classifying system trained using genetic algorithms can obtain a higher partial area under the receiver operating characteristic curve than implementing a single classifier.

Signalling Paediatric Side Effects using an Ensemble of Simple Study Designs

no code implementations2 Sep 2014 Jenna M. Reps, Jonathan M. Garibaldi, Uwe Aickelin, Daniele Soria, Jack E. Gibson, Richard B. Hubbard

Conclusion: This research shows that it is possible to exploit the mechanism of causality and presents a framework for signalling adverse drug reactions effectively.

Specificity

Cannot find the paper you are looking for? You can Submit a new open access paper.