no code implementations • 21 Jun 2022 • Cooper J. Mellema, Kevin P. Nguyen, Alex Treacher, Aixa Andrade Hernandez, Albert A. Montillo
Parkinsons disease (PD) is a movement disorder and the second most common neurodengerative disease but despite its relative abundance, there are no clinically accepted neuroimaging biomarkers to make prognostic predictions or differentiate between the similar atypical neurodegenerative diseases Multiple System Atrophy and Progressive Supranuclear Palsy.
no code implementations • 23 Feb 2022 • Kevin P. Nguyen, Albert Montillo
We propose a general-purpose framework for Adversarially-Regularized Mixed Effects Deep learning (ARMED) models through non-intrusive additions to existing neural networks: 1) an adversarial classifier constraining the original model to learn only cluster-invariant features, 2) a random effects subnetwork capturing cluster-specific features, and 3) an approach to apply random effects to clusters unseen during training.
no code implementations • 25 Nov 2019 • Cooper J. Mellema, Alex Treacher, Kevin P. Nguyen, Albert Montillo
Connectivity features identified as important across all 3 atlas granularity levels include FC to the supplementary motor gyrus and language association cortex, regions associated with deficits in social and sensory processing in ASD.
no code implementations • 22 Nov 2019 • Vyom Raval, Kevin P. Nguyen, Ashley Gerald, Richard B. Dewey Jr., Albert Montillo
The primary aim of this study was to develop a model using clinical measures and biomechanical measures of gait and postural stability to predict an individual's PD progression over two years.
no code implementations • 17 Oct 2019 • Kevin P. Nguyen, Cherise Chin Fatt, Alex Treacher, Cooper Mellema, Madhukar H. Trivedi, Albert Montillo
This method is tested on a challenging task of predicting antidepressant treatment response from pre-treatment task-based fMRI and demonstrates a 26% improvement in performance in predicting response using augmented images.