no code implementations • 18 Mar 2024 • Junghun Chae, Roktaek Lim, Thomas L. P. Martin, Cheol-Min Ghim, Pan-Jun Kim
Through the modeling of rhythmic protein-protein and protein-DNA interactions and the mammalian circadian clock, our analysis reveals the effect of the relaxation dynamics beyond the time delay, which extends to the dampening of changes in the complex concentration with a reduction in the oscillation amplitude against the quasi-steady state.
1 code implementation • 26 Nov 2018 • Hang-Hyun Jo, Yeon Jeong Kim, Jae Kyoung Kim, Mathias Foo, David E. Somers, Pan-Jun Kim
We also find that previously-enigmatic, cyclic expression of positive arm components within the mammalian and insect clocks allows both a broad range of peak time differences between protein waveforms and the symmetries of the waveforms about the peak times.
no code implementations • 12 Mar 2018 • Seunghyeon Kim, Michael F. Fenech, Pan-Jun Kim
Furthermore, we find that selenium and other essential micronutrients can be subject to deficiency in plant-based diets, and suggest nutritionally-desirable dietary patterns.
