no code implementations • 11 Apr 2024 • Rosalia Ferraro, Jasmin Di Franco, Sergio Caserta, Stefano Guido
Recently, the effect of flow on cell spheroids has been investigated in the context of tumor invasion in interstitial space.
no code implementations • 9 Aug 2023 • Rosalia Ferraro, Sergio Caserta, Stefano Guido
The mechanical characterization of cell spheroids, one of the most widely used 3D biology models in vitro, is a hotspot of current research on the role played by the mechanical response of cells and tissues.
no code implementations • 10 Feb 2022 • Rosalia Ferraro, Flora Ascione, Prashant Dogra, Vittorio Cristini, Stefano Guido, Sergio Caserta
The assay was performed by using a chemotactic chamber to impose a controlled gradients of nutrients (glucose) on spheroids, mimicking the chemotactic stimuli naturally occurring in the proximity of blood vessels.