Search Results for author: Vittorio Fortino

Found 4 papers, 1 papers with code

Quantitative in vitro to in vivo extrapolation for human toxicology and drug development

no code implementations6 Jan 2024 Luca Cattelani, Giusy del Giudice, Angela Serra, Michele Fratello, Laura Aliisa Saarimäki, Vittorio Fortino, Antonio Federico, Periklis Tsiros, Marika Mannerström, Tarja Toimela, Tommaso Serchi, Iseult Lynch, Philip Doganis, Haralambos Sarimveis, Dario Greco

Traditional animal testing for toxicity is expensive, time consuming, ethically questioned, sometimes inaccurate because of the necessity to extrapolate from animal to human, and in most cases not formally validated according to modern standards.

Dual-stage optimizer for systematic overestimation adjustment applied to multi-objective genetic algorithms for biomarker selection

no code implementations27 Dec 2023 Luca Cattelani, Vittorio Fortino

The challenge in biomarker discovery using machine learning from omics data lies in the abundance of molecular features but scarcity of samples.

feature selection Model Selection

Multi-Objective Genetic Algorithm for Multi-View Feature Selection

1 code implementation26 May 2023 Vandad Imani, Carlos Sevilla-Salcedo, Elaheh Moradi, Vittorio Fortino, Jussi Tohka

However, the use of multi-view data leads to an increase in high-dimensional data, which poses significant challenges for the prediction models that can lead to poor generalization.

feature selection

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