no code implementations • 21 Jun 2023 • Hina Shaheen, Roderick Melnik, the Alzheimer's Disease Neuroimaging Initiative
Therefore, in the present study, we developed and evaluated novel stochastic models for Abeta growth using ADNI data to predict the effect of astrocytes on AD progression in a clinical trial.
no code implementations • 17 Jun 2023 • Hina Shaheen, Roderick Melnik, Sundeep Singh
To better understand this interaction, we report a novel stochastic model where we analyze the positive feedback loop between A\beta and Ca^{+2} using ADNI data.
no code implementations • 6 Dec 2021 • Hina Shaheen, Roderick Melnik
Based on the prior striatal inhibitory model, we propose an extended BGTH model incorporating medium spine neurons (MSNs) and fast-spiking interneurons (FSIs) along with the effect of DBS.