Search Results for author: Hina Shaheen

Found 3 papers, 0 papers with code

Bayesian inference and role of astrocytes in amyloid-beta dynamics with modelling of Alzheimer's disease using clinical data

no code implementations21 Jun 2023 Hina Shaheen, Roderick Melnik, the Alzheimer's Disease Neuroimaging Initiative

Therefore, in the present study, we developed and evaluated novel stochastic models for Abeta growth using ADNI data to predict the effect of astrocytes on AD progression in a clinical trial.

Bayesian Inference

Data-driven Stochastic Model for Quantifying the Interplay Between Amyloid-beta and Calcium Levels in Alzheimer's Disease

no code implementations17 Jun 2023 Hina Shaheen, Roderick Melnik, Sundeep Singh

To better understand this interaction, we report a novel stochastic model where we analyze the positive feedback loop between A\beta and Ca^{+2} using ADNI data.

Deep brain stimulation with a computational model for the cortex-thalamus-basal-ganglia system and network dynamics of neurological disorders

no code implementations6 Dec 2021 Hina Shaheen, Roderick Melnik

Based on the prior striatal inhibitory model, we propose an extended BGTH model incorporating medium spine neurons (MSNs) and fast-spiking interneurons (FSIs) along with the effect of DBS.

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