no code implementations • 4 Mar 2024 • Akepogu Venkateshwarlu, Akshayveer, Sundeep Singh, Roderick Melnik
Despite much research done in this area, challenges remain in our better understanding of the behaviour of the cell in response to external stimuli, including the arrangement, quantity, and shape of organelles within the cell.
no code implementations • 26 Jan 2024 • Swadesh Pal, Roderick Melnik
Nonlocality is important in realistic mathematical models of physical and biological systems at small-length scales.
no code implementations • 3 Nov 2023 • Swadesh Pal, Malay Banerjee, Roderick Melnik
Patterns in a semiarid ecosystem are important because they directly and indirectly affect ecological processes, biodiversity, and ecosystem resilience.
no code implementations • 2 Oct 2023 • Sangeeta Saha, Swadesh Pal, Roderick Melnik
In a predator-prey interaction, there are many factors present which affect the growth of the species, either positively or negatively.
no code implementations • 21 Jun 2023 • Hina Shaheen, Roderick Melnik, the Alzheimer's Disease Neuroimaging Initiative
Therefore, in the present study, we developed and evaluated novel stochastic models for Abeta growth using ADNI data to predict the effect of astrocytes on AD progression in a clinical trial.
no code implementations • 17 Jun 2023 • Hina Shaheen, Roderick Melnik, Sundeep Singh
To better understand this interaction, we report a novel stochastic model where we analyze the positive feedback loop between A\beta and Ca^{+2} using ADNI data.
no code implementations • 6 Aug 2022 • Swadesh Pal, Roderick Melnik
We consider a fractional order network mathematical model to capture the influence of such memory effect on AD propagation.
no code implementations • 10 May 2022 • Thi Kim Thoa Thieu, Roderick Melnik
Working memory (WM) has been intensively used to enable the temporary storing of information for processing purposes, playing an important role in the execution of various cognitive tasks.
no code implementations • 19 Feb 2022 • Thi Kim Thoa Thieu, Roderick Melnik
Motivated by important applications of the integrate-and-fire of neurons in neuromorphic computing for bio-medical studies, the main focus of the present work is on the analysis of the effects of additive and multiplicative types of random input currents together with a random refractory period on a leaky integrate-and-fire (LIF) synaptic conductance neuron model.
no code implementations • 24 Dec 2021 • Thi Kim Thoa Thieu, Roderick Melnik
Our brain is a complex information processing network in which the nervous system receives information from the environment to quickly react to incoming events or learns from experience to sharp our memory.
no code implementations • 22 Dec 2021 • Swadesh Pal, Roderick Melnik
Higher toxic concentrations of amyloid-beta and tau proteins destroy the brain cell.
no code implementations • 6 Dec 2021 • Hina Shaheen, Roderick Melnik
Based on the prior striatal inhibitory model, we propose an extended BGTH model incorporating medium spine neurons (MSNs) and fast-spiking interneurons (FSIs) along with the effect of DBS.