Search Results for author: Roderick Melnik

Found 12 papers, 0 papers with code

Piezoelectricity and flexoelectricity in biological cells: The role of cell structure and organelles

no code implementations4 Mar 2024 Akepogu Venkateshwarlu, Akshayveer, Sundeep Singh, Roderick Melnik

Despite much research done in this area, challenges remain in our better understanding of the behaviour of the cell in response to external stimuli, including the arrangement, quantity, and shape of organelles within the cell.

Nonlocal Models in Biology and Life Sciences: Sources, Developments, and Applications

no code implementations26 Jan 2024 Swadesh Pal, Roderick Melnik

Nonlocality is important in realistic mathematical models of physical and biological systems at small-length scales.

The Role of Soil Surface in a Sustainable Semiarid Ecosystem

no code implementations3 Nov 2023 Swadesh Pal, Malay Banerjee, Roderick Melnik

Patterns in a semiarid ecosystem are important because they directly and indirectly affect ecological processes, biodiversity, and ecosystem resilience.

Management

The analysis of the impact of fear in the presence of additional food and prey refuge with nonlocal predator-prey models

no code implementations2 Oct 2023 Sangeeta Saha, Swadesh Pal, Roderick Melnik

In a predator-prey interaction, there are many factors present which affect the growth of the species, either positively or negatively.

Bayesian inference and role of astrocytes in amyloid-beta dynamics with modelling of Alzheimer's disease using clinical data

no code implementations21 Jun 2023 Hina Shaheen, Roderick Melnik, the Alzheimer's Disease Neuroimaging Initiative

Therefore, in the present study, we developed and evaluated novel stochastic models for Abeta growth using ADNI data to predict the effect of astrocytes on AD progression in a clinical trial.

Bayesian Inference

Data-driven Stochastic Model for Quantifying the Interplay Between Amyloid-beta and Calcium Levels in Alzheimer's Disease

no code implementations17 Jun 2023 Hina Shaheen, Roderick Melnik, Sundeep Singh

To better understand this interaction, we report a novel stochastic model where we analyze the positive feedback loop between A\beta and Ca^{+2} using ADNI data.

Non-Markovian behaviour and the dual role of astrocytes in Alzheimer's disease development and propagation

no code implementations6 Aug 2022 Swadesh Pal, Roderick Melnik

We consider a fractional order network mathematical model to capture the influence of such memory effect on AD propagation.

Effects of random inputs and short-term synaptic plasticity in a LIF conductance model for working memory applications

no code implementations10 May 2022 Thi Kim Thoa Thieu, Roderick Melnik

Working memory (WM) has been intensively used to enable the temporary storing of information for processing purposes, playing an important role in the execution of various cognitive tasks.

Effects of noise on leaky integrate-and-fire neuron models for neuromorphic computing applications

no code implementations19 Feb 2022 Thi Kim Thoa Thieu, Roderick Melnik

Motivated by important applications of the integrate-and-fire of neurons in neuromorphic computing for bio-medical studies, the main focus of the present work is on the analysis of the effects of additive and multiplicative types of random input currents together with a random refractory period on a leaky integrate-and-fire (LIF) synaptic conductance neuron model.

Coupled effects of channels and synaptic dynamics in stochastic modelling of healthy and Parkinson's-disease-affected brains

no code implementations24 Dec 2021 Thi Kim Thoa Thieu, Roderick Melnik

Our brain is a complex information processing network in which the nervous system receives information from the environment to quickly react to incoming events or learns from experience to sharp our memory.

Deep brain stimulation with a computational model for the cortex-thalamus-basal-ganglia system and network dynamics of neurological disorders

no code implementations6 Dec 2021 Hina Shaheen, Roderick Melnik

Based on the prior striatal inhibitory model, we propose an extended BGTH model incorporating medium spine neurons (MSNs) and fast-spiking interneurons (FSIs) along with the effect of DBS.

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